Anatomy

Download Platelets by Alan D. Michelson PDF

By Alan D. Michelson

Platelets — winner of a 2013 hugely counseled BMA scientific booklet Award for inner drugs — is the definitive present resource of state of the art wisdom approximately platelets and covers the whole box of platelet biology, pathophysiology, and medical medication. lately there was a speedy enlargement of data in either simple biology and the scientific method of platelet-related ailments together with thrombosis and hemorrhage. Novel platelet functionality assessments, medications, blood financial institution garage equipment, and gene treatments were included into sufferer care or are in improvement. This booklet attracts all this knowledge right into a unmarried, complete and authoritative resource.

  • Highly counseled BMA scientific booklet Award 2013: inner Medicine
  • Comprehensive and definitive resource of data approximately platelets for clinicians, pathologists and scientists
  • Integrates the total box of platelet biology, pathophysiology, and medical medicine
  • Full colour reference comprising sixty four chapters, 1400 pages, and 16,000 references
  • Contributions from 126 international leaders of their fields
  • New chapters on subject matters reminiscent of the rules of platelet existence span, platelet microRNAs, GPVI and CLEC-2, tracking of antiplatelet remedy, novel antiplatelet remedy, and making platelets ex vivo

Show description

Anatomy

Download Penguin Biology by Lloyd S. Davis,John T. Darby PDF

By Lloyd S. Davis,John T. Darby

Penguin Biology is the 1st broad-based selection of organic and ecological stories of those precise birds to be released in view that 1975. issues have given that turn into huge ecological hypotheses, now not species-specific descriptions, and new know-how has taken observations into the oceanic depths. Penguin Biology exhibits new options and the purposes mad of them in modern organic and evolutionary theory.

Penguin Biology is a useful reference for ornithologists, animal behaviorists, animal physiologists, marine zoologists, marine ecologists, evolutionary biologists, and Antarctic researchers.

  • Major subject matters lined comprise Breeding, feeding, and foraging
  • Behavior and evolution
  • Energetics and physiology
  • New fossil material

Show description

Anatomy

Download Problem-Based Anatomy E-Book by Craig A. Canby PDF

By Craig A. Canby

This new textual content incorporates a compilation of medical situations that use a problem-based method of illustrate the medical importance of the subdisciplines of anatomy. Seven separate sections current anatomy in a nearby layout. every one part includes a number of medical circumstances that stroll you thru a variety of sufferers' presentation, heritage and actual exam details, laboratory and diagnostic try effects, analysis, and therapy. a chain of comparable questions and accompanying solutions keep on with every one scientific situation, probing your figuring out of the scientific concerns correct to that physique region.

  • Features greater than eighty scientific eventualities that advertise interactive studying and construct a starting place of information for scientific perform.
  • Presents details in seven sections to correspond with a nearby method of anatomy: head and neck, again, thorax, pelvis and perineum, higher extremity, and reduce extremity.
  • Covers the subdisciplines of anatomy together with anatomic pathology · mobilephone biology · embryology · gross anatomy · histology · neuroanatomy · and radiologic anatomy.
  • Includes references to Gray's Anatomy for college students, and follows a parallel association, making it effortless to exploit either books together.

Show description

Anatomy

Download The Role of Pendrin in Health and Disease: Molecular and by Silvia Dossena,Markus Paulmichl PDF

By Silvia Dossena,Markus Paulmichl

This booklet studies the present country of information at the genetics, molecular biology and body structure of pendrin, with a selected specialize in pendrin disorder and the implications for human health. 

Pendrin is a membrane delivery protein expressed within the thyroid, internal ear, kidney and airlines, and was once lately present in quite a few different tissues and organs. Pendrin malfunction could cause a genetic affliction referred to as Pendred syndrome or non-syndromic deafness.

The ebook offers an intensive description of the multifaceted position of pendrin in human overall healthiness and ailment. As such, it bargains a useful device for body structure and pathology researchers, whereas additionally supplying crucial assistance for otorhinolaryngologists and endocrinologists within the prognosis of Pendred syndrome and pendrin-related deafness.

Show description

Anatomy

Download Hung Like an Argentine Duck: A Journey Back in Time to the by John Long PDF

By John Long

we know concerning the birds and the bees, yet what concerning the old placoderm fishes and the dinosaurs? The historical past of intercourse is as previous as lifestyles itself-and as advanced and mysterious. And regardless of centuries of analysis there's continuously extra to understand. In 2008, paleontologist John A. lengthy and a workforce of researchers printed their discovery of a placoderm fish fossil, referred to as "the mom fish," which at 380 million years previous printed the oldest vertebrate embryo-the earliest recognized instance of inner fertilization. As lengthy explains, this locate ended in the reexamination of numerous fish fossils and the invention of formerly undetected embryos. therefore, placoderms are actually thought of to be the 1st species to have had intimate sexual copy or intercourse as we all know it-sort of. encouraged by way of this wonderful locate, lengthy begun a quest to discover the paleontological and evolutionary heritage of copulation and insemination. In Hung Like An Argentine Duck, he is taking readers on an enjoyable and vigorous journey throughout the intercourse lives of historical fish and exposes the weird mating behavior of arthropods, tortoises, or even a well-endowed (16.5 inches!) Argentine Duck. lengthy discusses those major discoveries along what we all know approximately reproductive biology and evolutionary conception, utilizing the fossil checklist to supply a provocative account of prehistoric intercourse. Hung Like An Argentine Duck additionally explores interesting revelations approximately animal copy, from gay penguins to monogamous seahorses to the problems of dinosaur romance and the way sexual organs in historic shark-like fishes truly relate to our personal sexual anatomy. Hung Like An Argentine Duck is Long's personal tale of what it truly is prefer to be part of a discovery that rewrites evolutionary background in addition to a fully rollicking advisor to intercourse through the a long time. "John lengthy is well known because the discoverer of the earliest proof for inner fertilisation. In a publication encompassing 380 million years of sexual evolution, he lays the total importance of his discoveries in interesting context." - tim Flannery "You are actually protecting a compromise among a publication so you might hold hidden within an opaque bag, and a sober decent medical treatise. it is a deliciously written account of the evolution of intercourse, in all of its extraordinary manifestations. learn, blush, and enjoy!" - Jared Diamond, Professor of Geography at UCLA, Pulitzer-Prize-winning writer of weapons, Germs, and metal "I shall by no means consider an analogous approximately geese back. Or fish. this is often first-class technological know-how informed with brilliance and aptitude. learn and be astounded." - Robyn Williams 'John lengthy breaks new flooring in our realizing of the origins of intercourse because it is written within the fossil checklist. utilizing well-preserved specimens he has labored on for greater than 20 years, he reconstructs an in depth four hundred million yr background within which survival of not just the easiest, yet sexiest, keeps to dominate all species, together with people' - Carmelo Amalfi, technological know-how writer.

Show description

Anatomy

Download Validation of Alternative Methods for Toxicity Testing by Chantra Eskes,Maurice Whelan PDF

By Chantra Eskes,Maurice Whelan

This publication offers info on top practices and new considering in regards to the validation of other tools for toxicity trying out. It covers the validation of experimental and computational tools and built-in ways to checking out and evaluation. Validation options are mentioned for tactics utilising the most recent applied sciences comparable to tissue-on-a-chip platforms, stem cells and transcriptomics, and for tactics derived from pathway-based recommendations in toxicology.

 

Validation of other equipment for Toxicity checking out is divided into sections, within the first, sensible insights are given at the cutting-edge and on ways that experience ended in effectively verified and approved substitute tools. the second one part makes a speciality of the evolution of validation rules and perform which are essential to confirm fit-for-purpose validation that has the best effect on overseas regulatory popularity of other equipment. during this context validation must maintain velocity with the massive clinical developments being made in toxicology, the supply of subtle instruments and strategies that may be utilized in quite a few methods, and the expanding societal and regulatory calls for for higher protection evaluation.

 

This publication could be an invaluable source for scientists within the box of toxicology, either from and academia, constructing new try tools, thoughts or strategies, in addition to Governmental and regulatory specialists attracted to figuring out the foundations and practicalities of validation of other equipment for toxicity testing.

 

Show description

Anatomy

Download Hearing: An Introduction to Psychological and Physiological by Stanley A. Gelfand,Stanley Gelfand PDF

By Stanley A. Gelfand,Stanley Gelfand

Brimming with greater than greater than 1700 references, this reader-friendly and largely revised Fourth variation will end up worthy to teachers and scholars alike-providing a unified method of the anatomical, physiological, and perceptual features of audition with up-to-date chapters at the most modern advancements within the field.

Show description

Anatomy

Download Genetic Influences on Response to Drug Treatment for Major by Janusz K. Rybakowski,Alessandro Serretti PDF

By Janusz K. Rybakowski,Alessandro Serretti

Written via international specialists, this e-book presents a contemporary complete perception into the pharmacogenetics of therapy of significant psychoses: schizophrenia, bipolar illness and melancholy. The pharmacogenomics of 3 different types of crucial psychiatric medicines, antipsychotics, antidepressants and temper stabilizers, has been up-to-date and reviewed.

Some promising instructions and views for destiny examine in pharmacogenetics in significant psychoses are indicated. they're, between others, hooked up with the advance of latest equipment in molecular genetics and with linking pharmacogenetics evaluation with biomarkers, together with neuroimaging ones. eventually, the makes an attempt to exploit pharmacogenetics of antipsychotic, antidepressant and mood-stabilizing medicinal drugs in perform are offered. New pharmacogenetic instruments may well tremendously give a contribution to introducing customized medication into psychiatric medical practice. 

Show description

Anatomy

Download Patient-Specific Modeling of the Cardiovascular System: by Roy C.P. Kerckhoffs PDF

By Roy C.P. Kerckhoffs

Peter Hunter Computational body structure for the cardiovascular process is coming into a brand new and intriguing section of scientific software. Biophysically established versions of the human center and circulate, in response to patient-specific anatomy but in addition educated by way of po- lation atlases and incorporating loads of mechanistic realizing on the cellphone, tissue, and organ degrees, supply the possibility of evidence-based analysis and remedy of heart problems. The scientific worth of patient-specific modeling is easily illustrated in program components the place model-based interpretation of medical photos permits a extra specified research of affliction techniques than can rather be completed. for instance, Chap. 6 during this quantity, via Speelman et al. , bargains with the very tricky challenge of attempting to are expecting no matter if and whilst an stomach aortic aneurysm may well burst. This calls for computerized segmentation of the vascular geometry from magnetic re- nance photos and finite point research of wall tension utilizing huge deformation elasticity conception utilized to the geometric version produced from the segmentation. The time-varying common and shear pressure performing on the arterial wall is anticipated from the arterial strain and circulation distributions. Thrombus formation is pointed out as a probably vital contributor to replaced fabric houses of the arterial wall. knowing how the wall adapts and remodels its fabric homes within the face of alterations in either the strain loading and blood components linked to infl- matory approaches (IL6, CRP, MMPs, etc.

Show description